The menstrual cycle is so much more than your period.
There are four phases - menstrual, follicular, ovulation & luteal. During these phases, oestrogen, progesterone & testosterone rise and fall.
In a healthy female, these hormonal shifts are predicable. And yet so little of our life is built around this important cycle.
These shifting hormones impact how we think and feel.
Hormones are chemical messengers that regulate how the body works. Female sex hormones play a crucial role in regulating the menstrual cycle, fertility, mood, energy, and overall well-being. Crucially, they impact how productive we feel.
Oestrogen
Often called the "primary female hormone," estrogen is a group of hormones which regulate the menstrual cycle, support reproductive health, and impact mood, bone strength, and skin health.
Boosts energy, creativity & communication.
Progesterone
This hormone dominates the second half of the cycle, preparing the body for pregnancy. It has a calming effect, supporting sleep, reducing anxiety, and balancing estrogen’s stimulating effects.
Boosts reflection & focus.
Testosterone
While known as a "male hormone," testosterone is essential for women too. It fuels libido, muscle strength and cognitive sharpness, peaking around the middle of your cycle.
Boosts energy and motivation.
We’ve translated this science into a tool for all women to use.
Taking the cutting-edge insights on how hormones shape our brains, our proprietary algorithm distills this information into actionable insights.
Phase maps how six key elements of energy and cognition are shifting daily: your communication, energy, motivation, creativity, reflection and focus.
This is then presented on your daily radar and in the elements shown across your calendar and extensions.
Our clinical team is made up of some of the leading minds in neuroendocrinology, psychology and women’s health.
Built by leading researchers in cutting edge science.
Our technologies are grounded in cutting edge research from the past 20 years. Here are selection of papers, some written by our advisors, and others from the broader community, which provide the scientific bedrock for Phase.
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Le J, Thomas N, Gurvich C. Cognition, the menstrual cycle, and premenstrual disorders: A review. Brain Sciences. 2020;10(4):198.
Ronca F, Blodgett J, Bruinvels G, Lowery M, Raviraj M, Sandhar G, et al. Attentional, anticipatory and spatial cognition fluctuate throughout the menstrual cycle: Potential implications for female sport. Neuropsychologia. 2024:108909.
Pletzer B, Harris T-A, Scheuringer A, Hidalgo-Lopez E. The cycling brain: menstrual cycle related fluctuations in hippocampal and fronto-striatal activation and connectivity during cognitive tasks. Neuropsychopharmacology. 2019;44(11):1867-75.
Albert KM, Newhouse PA. Estrogen, stress, and depression: cognitive and biological interactions. Annual review of clinical psychology. 2019;15:399-423.
Cui J, Shen Y, Li R. Estrogen synthesis and signaling pathways during aging: from periphery to brain. Trends in molecular medicine. 2013;19(3):197-209.
Eyster KM. The estrogen receptors: an overview from different perspectives. Estrogen Receptors: Methods and Protocols. 2016:1-10.
Mosconi L, Nerattini M, Matthews DC, Jett S, Andy C, Williams S, et al. In vivo brain estrogen receptor density by neuroendocrine aging and relationships with cognition and symptomatology. Scientific Reports. 2024;14(1):12680.
Asavasupreechar T, Saito R, Miki Y, Edwards DP, Boonyaratanakornkit V, Sasano H. Systemic distribution of progesterone receptor subtypes in human tissues. The Journal of steroid biochemistry and molecular biology. 2020;199:105599.
Gravelsins L, Zhao S, Einstein G. Hormonal contraception and cognition: Considering the influence of endogenous ovarian hormones and genes for clinical translation. Frontiers in Neuroendocrinology. 2023;70:101067.
